petBrain: a new pipeline for amyloid, Tau tangles and neurodegeneration quantification using PET and MRI

Abstract Introduction Quantification of amyloid plaques (A), neurofibrillary tangles (T2), and neurodegeneration (N) using PET and MRI is critical for Alzheimer’s disease (AD) diagnosis and prognosis. Existing pipelines face limitations regarding processing time, tracer variability handling, and mul...

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Hauptverfasser:	Pierrick Coupé, Boris Mansencal, Floréal Morandat, Sergio Morell-Ortega, Nicolas Villain, Jose V. Manjón, Vincent Planche
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2025-09-01
Schriftenreihe:	Alzheimer’s Research & Therapy
Schlagworte:	A/T/N model Image processing MRI segmentation Centiloid Centaur
Online-Zugang:	https://doi.org/10.1186/s13195-025-01839-y
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