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petBrain: a new pipeline for amyloid, Tau tangles and neurodegeneration quantification using PET and MRI

Abstract Introduction Quantification of amyloid plaques (A), neurofibrillary tangles (T2), and neurodegeneration (N) using PET and MRI is critical for Alzheimer’s disease (AD) diagnosis and prognosis. Existing pipelines face limitations regarding processing time, tracer variability handling, and mul...

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Principais autores: Pierrick Coupé, Boris Mansencal, Floréal Morandat, Sergio Morell-Ortega, Nicolas Villain, Jose V. Manjón, Vincent Planche
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-09-01
Serier:Alzheimer’s Research & Therapy
Fag:
A/T/N model
Image processing
MRI segmentation
Centiloid
Centaur
Online adgang:https://doi.org/10.1186/s13195-025-01839-y
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