Exosomal Linc00969 induces trastuzumab resistance in breast cancer by increasing HER-2 protein expression and mRNA stability by binding to HUR

Abstract Background Breast cancer (BC) is the most common malignant disease in female patients worldwide. In HER-2+ BC patients, trastuzumab therapy is associated with a better prognosis. However, many HER-2+ BC patients experience recurrence or metastasis because of trastuzumab resistance. The mech...

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Bibliografische gegevens

Hoofdauteurs:	Cuiwei Liu, Chong Lu, Lamu Yixi, Jiaxing Hong, Fang Dong, Shengnan Ruan, Ting Hu, Xiangwang Zhao
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	BMC 2023-10-01
Reeks:	Breast Cancer Research
Onderwerpen:	Exosomes Linc00969 Breast cancer HER-2 HUR
Online toegang:	https://doi.org/10.1186/s13058-023-01720-6
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