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In Vitro Permeability Study of Homotaurine Using a High-Performance Liquid Chromatography with Fluorescence Detection Pre-Column Derivatization Method

Homotaurine (HOM) is considered a promising drug for the treatment of Alzheimer’s and other neurodegenerative diseases. In the present work, a new high-performance liquid chromatography with fluorescence detection (HPLC–FLD) (λex. = 340 nm and λem. = 455 nm) method was developed and validated for th...

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Huvudupphov: Marianna Ntorkou, Eleni Tsanaktsidou, Konstantina Chachlioutaki, Dimitrios G. Fatouros, Catherine K. Markopoulou
Materialtyp: Artigo
Språk:Inglês
Utgiven: MDPI AG 2023-10-01
Serie:Molecules
Ämnen:
homotaurine
derivatization
HPLC–FLD
CNS permeability study
Länkar:https://www.mdpi.com/1420-3049/28/20/7086
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