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Efficacy of a platinum-based chemotherapy rechallenge for platinum-sensitive recurrence after PARP inhibitor maintenance

Objective: Platinum-free interval (PFI) is the period from the end of platinum-based chemotherapy to the date of recurrence. If the PFI is > 6 months, a platinum-based chemotherapy rechallenge is considered; however, its efficacy after poly adenosine 5′-diphosphate-ribose polymerase (PARP) inhibitor...

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Principais autores: Takehiro Nakao, Kenichi Harano, Masashi Wakabayashi, Yoichi Naito, Hiroshi Tanabe, Toru Mukohara
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2024-10-01
coleção:Gynecologic Oncology Reports
Assuntos:
Maintenance
Ovarian cancer
PARP inhibitor
Platinum-free interval
Rechallenge
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2352578924001619
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