Apolipoprotein A1 (CSL112) Increases Lecithin-Cholesterol Acyltransferase Levels in HDL Particles and Promotes Reverse Cholesterol Transport

Summary: Although high-density lipoprotein (HDL) cholesterol is inversely correlated with cardiovascular risk, an emerging paradigm is focused on increasing reverse cholesterol transport (RCT) and HDL function via apolipoprotein A1 (ApoA1). The objective of this study was to investigate the effect o...

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Principais autores:	Rommel A. Mathias, PhD, Elena Velkoska, PhD, Svetlana A. Didichenko, PhD, Brandon H. Greene, PhD, Xiahui Tan, PhD, Alexey V. Navdaev, PhD, Heidi L. Collins, PhD, Steven J. Adelman, PhD, Kyal Young, BSc, Andreas Gille, MD, PhD, Danielle Duffy, MD, C. Michael Gibson, MSc, MD, Matthias Pelzing, PhD, Bronwyn A. Kingwell, PhD
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2025-04-01
coleção:	JACC: Basic to Translational Science
Assuntos:	acute myocardial infarction CSL112 high-density lipoprotein lecithin-cholesterol acyl transferase proteome
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2452302X24003978
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