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In vitro study: HIF-1α-dependent glycolysis enhances NETosis in hypoxic conditions

BackgroundHypoxia plays a pivotal role in modulating immune responses, especially in neutrophils, which are essential components of the innate immune system. Hypoxia-inducible factor (HIF)-1α, a key transcription factor in hypoxic adaptation, regulates cellular metabolism and inflammatory responses....

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Bibliografische gegevens
Hoofdauteurs: Yi Ye, Yanjun Wang, Qiying Xu, Juanli Liu, Ziqi Yang, Tana Wuren, Ri-Li Ge
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2025-04-01
Reeks:Frontiers in Immunology
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Online toegang:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1583587/full
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