In vitro study: HIF-1α-dependent glycolysis enhances NETosis in hypoxic conditions

BackgroundHypoxia plays a pivotal role in modulating immune responses, especially in neutrophils, which are essential components of the innate immune system. Hypoxia-inducible factor (HIF)-1α, a key transcription factor in hypoxic adaptation, regulates cellular metabolism and inflammatory responses....

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Yi Ye, Yanjun Wang, Qiying Xu, Juanli Liu, Ziqi Yang, Tana Wuren, Ri-Li Ge
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Frontiers Media S.A. 2025-04-01
Sarja:	Frontiers in Immunology
Aiheet:	HIF-1α glycolysis neutrophil extracellular traps hypoxia neutrophils
Linkit:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1583587/full
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