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Monitoring GPCR conformation with GFP-inspired dyes

Summary: Solvatochromic compounds have emerged as valuable environment-sensitive probes for biological research. Here we used thiol-reactive solvatochromic analogs of the green fluorescent protein (GFP) chromophore to track conformational changes in two proteins, recoverin and the A2A adenosine rece...

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Hlavní autoři: Anatoliy Belousov, Ivan Maslov, Philipp Orekhov, Polina Khorn, Pavel Kuzmichev, Nadezhda Baleeva, Vladislav Motov, Andrey Bogorodskiy, Svetlana Krasnova, Konstantin Mineev, Dmitry Zinchenko, Evgeni Zernii, Valentin Ivanovich, Sergei Permyakov, Johan Hofkens, Jelle Hendrix, Vadim Cherezov, Thomas Gensch, Alexander Mishin, Mikhail Baranov, Alexey Mishin, Valentin Borshchevskiy
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2024-08-01
Edice:iScience
Témata:
Biochemistry
Structural biology
Biophysics
On-line přístup:http://www.sciencedirect.com/science/article/pii/S2589004224016912
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