IL6 receptor inhibitors: exploring the therapeutic potential across multiple diseases through drug target Mendelian randomization

BackgroundHigh interleukin-6 levels correlate with diseases like cancer, autoimmune disorders, and infections. IL-6 receptor inhibitors (IL-6Ri), used for rheumatoid arthritis and COVID-19, may have wider uses. We apply drug-target Mendelian Randomization (MR) to study IL-6Ri’s effects.MethodTo simu...

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Autors principals:	Chong Fu, Longquan Wang, Wenjiao Cai
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2024-08-01
Col·lecció:	Frontiers in Immunology
Matèries:	IL-6 receptor Mendelian randomization idiopathic pulmonary fibrosis Parkinson’s disease type 2 diabetes
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1452849/full
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