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Contraction-Induced Loss of Plasmalemmal Electrophysiological Function Is Dependent on the Dystrophin Glycoprotein Complex

Weakness and atrophy are key features of Duchenne muscular dystrophy (DMD). Dystrophin is one of the many proteins within the dystrophin glycoprotein complex (DGC) that maintains plasmalemmal integrity and cellular homeostasis. The dystrophin-deficient mdx mouse is also predisposed to weakness, part...

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Autori principali: Cory W. Baumann, Angus Lindsay, Sylvia R. Sidky, James M. Ervasti, Gordon L. Warren, Dawn A. Lowe
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021-10-01
Serie:Frontiers in Physiology
Soggetti:
eccentric contractions
electromyography
injury
muscular dystrophy
strength
Accesso online:https://www.frontiersin.org/articles/10.3389/fphys.2021.757121/full
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