Tuft cells are required for a rhinovirus-induced asthma phenotype in immature mice

Infection of immature mice with rhinovirus (RV) induces an asthma-like phenotype consisting of type 2 inflammation, mucous metaplasia, eosinophilic inflammation, and airway hyperresponsiveness that is dependent on IL-25 and type 2 innate lymphoid cells (ILC2s). Doublecortin-like kinase 1–positive (D...

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主要な著者:	Yiran Li, Mingyuan Han, Shilpi Singh, Haley A. Breckenridge, Jordan E. Kreger, Claudia C. Stroupe, Daniel A. Sawicky, Shiuhyang Kuo, Adam M. Goldsmith, Fang Ke, Anukul T. Shenoy, J. Kelley Bentley, Ichiro Matsumoto, Marc B. Hershenson
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Clinical investigation 2024-01-01
シリーズ:	JCI Insight
主題:	Pulmonology
オンライン･アクセス:	https://doi.org/10.1172/jci.insight.166136
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