Tuft cells are required for a rhinovirus-induced asthma phenotype in immature mice

Infection of immature mice with rhinovirus (RV) induces an asthma-like phenotype consisting of type 2 inflammation, mucous metaplasia, eosinophilic inflammation, and airway hyperresponsiveness that is dependent on IL-25 and type 2 innate lymphoid cells (ILC2s). Doublecortin-like kinase 1–positive (D...

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Bibliografische gegevens
Hoofdauteurs:	Yiran Li, Mingyuan Han, Shilpi Singh, Haley A. Breckenridge, Jordan E. Kreger, Claudia C. Stroupe, Daniel A. Sawicky, Shiuhyang Kuo, Adam M. Goldsmith, Fang Ke, Anukul T. Shenoy, J. Kelley Bentley, Ichiro Matsumoto, Marc B. Hershenson
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	American Society for Clinical investigation 2024-01-01
Reeks:	JCI Insight
Onderwerpen:	Pulmonology
Online toegang:	https://doi.org/10.1172/jci.insight.166136
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Tuft cells are required for a rhinovirus-induced asthma phenotype in immature mice

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