Myrislignan targets extracellular signal-regulated kinase (ERK) and modulates mitochondrial function to dampen osteoclastogenesis and ovariectomy-induced osteoporosis
Abstract Background Activated osteoclasts cause excessive bone resorption, and disrupt bone homeostasis, leading to osteoporosis. The extracellular signal-regulated kinase (ERK) signaling is the classical pathway related to osteoclast differentiation, and mitochondrial reactive oxygen species are cl...
Na minha lista:
| Principais autores: | , , , , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2023-11-01
|
| coleção: | Journal of Translational Medicine |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1186/s12967-023-04706-2 |
| Tags: |
Sem tags, seja o primeiro a adicionar uma tag!
|
