Control of intracellular pH and bicarbonate by CO2 diffusion into human sperm
Abstract The reaction of CO2 with H2O to form bicarbonate (HCO3 −) and H+ controls sperm motility and fertilization via HCO3 −-stimulated cAMP synthesis. A complex network of signaling proteins participates in this reaction. Here, we identify key players that regulate intracellular pH (pHi) and HCO3...
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| Principais autores: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Portfolio
2023-09-01
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| coleção: | Nature Communications |
| Acesso em linha: | https://doi.org/10.1038/s41467-023-40855-0 |
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