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The endothelial tumor suppressor p53 is essential for venous thrombus formation in aged mice

Abstract: Venous thromboembolism (VTE) is a leading cause of morbidity and mortality in elderly people. Increased expression of tumor suppressor protein 53 (p53) has been implicated in vascular senescence. Here, we examined the importance of endothelial p53 for venous thrombosis and whether endothel...

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Bibliografische gegevens
Hoofdauteurs: Magdalena L. Bochenek, Tobias Bauer, Rajinikanth Gogiraju, Yona Nadir, Amrit Mann, Tanja Schönfelder, Leonie Hünig, Benjamin Brenner, Thomas Münzel, Philip Wenzel, Stavros Konstantinides, Katrin Schäfer
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2018-06-01
Reeks:Blood Advances
Online toegang:http://www.sciencedirect.com/science/article/pii/S2473952920309927
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