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The Multidrug Efflux Regulator AcrR of Escherichia coli Responds to Exogenous and Endogenous Ligands To Regulate Efflux and Detoxification

ABSTRACT The transcriptional repressor AcrR is the main regulator of the multidrug efflux pump AcrAB-TolC, which plays a major role in antibiotic resistance and cell physiology in Escherichia coli and other Enterobacteriaceae. However, it remains unknown which ligands control the function of AcrR. T...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Dana E. Harmon, Cristian Ruiz
Hōputu: Artigo
Reo:Inglês
I whakaputaina: American Society for Microbiology 2022-12-01
Rangatū:mSphere
Ngā marau:
Urunga tuihono:https://journals.asm.org/doi/10.1128/msphere.00474-22
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