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A TOR (target of rapamycin) and nutritional phosphoproteome of fission yeast reveals novel targets in networks conserved in humans

Fluctuations in TOR, AMPK and MAP-kinase signalling maintain cellular homeostasis and coordinate growth and division with environmental context. We have applied quantitative, SILAC mass spectrometry to map TOR and nutrient-controlled signalling in the fission yeast Schizosaccharomyces pombe. Phospho...

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Principais autores: Lenka Halova, David Cobley, Mirita Franz-Wachtel, Tingting Wang, Kaitlin R. Morrison, Karsten Krug, Nicolas Nalpas, Boris Maček, Iain M. Hagan, Sean J. Humphrey, Janni Petersen
Format: Artigo
Sprog:Inglês
Udgivet: The Royal Society 2021-04-01
Serier:Open Biology
Fag:
TORC1
TORC2
nitrogen stress
phosphoproteome
fission yeast Schizosaccharomyces pombe
Byr1 MAPKK
Online adgang:https://royalsocietypublishing.org/doi/10.1098/rsob.200405
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