Pseudomonas aeruginosa GidA modulates the expression of catalases at the posttranscriptional level and plays a role in virulence

Pseudomonas aeruginosa gidA, which encodes a putative tRNA-modifying enzyme, is associated with a variety of virulence phenotypes. Here, we demonstrated that P. aeruginosa gidA is responsible for the modifications of uridine in tRNAs in vivo. Loss of gidA was found to have no impact on the mRNA leve...

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Auteurs principaux:	Thanyaporn Srimahaeak, Narumon Thongdee, Jurairat Chittrakanwong, Sopapan Atichartpongkul, Juthamas Jaroensuk, Kamonwan Phatinuwat, Narumon Phaonakrop, Janthima Jaresitthikunchai, Sittiruk Roytrakul, Skorn Mongkolsuk, Mayuree Fuangthong
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2023-01-01
Collection:	Frontiers in Microbiology
Sujets:	Pseudomonas aeruginosa tRNA modification oxidative stress gidA U34 modification catalases
Accès en ligne:	https://www.frontiersin.org/articles/10.3389/fmicb.2022.1079710/full
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