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The H2TH-like motif of the Escherichia coli multifunctional protein KsgA is required for DNA binding involved in DNA repair and the suppression of mutation frequencies

Abstract Background DNA oxidatively damaged by reactive oxygen species is repaired by base excision repair (BER) pathway proteins, with DNA glycosylases removing damaged or mismatched bases in the first step of BER. KsgA is a multifunctional protein that exhibits the activities of two enzymes, DNA g...

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Principais autores: Yuichiro Hayashi, Masafumi Funakoshi, Kaname Hirosawa, Qiu-Mei Zhang-Akiyama
Format: Artigo
Jezik:Inglês
Izdano: BMC 2023-04-01
Serija:Genes and Environment
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Online dostop:https://doi.org/10.1186/s41021-023-00266-5
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