A single-dose circular RNA vaccine prevents Zika virus infection without enhancing dengue severity in mice

Abstract Antibody-dependent enhancement (ADE) is a potential concern for the development of Zika virus (ZIKV) vaccines. Cross-reactive but poorly neutralizing antibodies, usually targeting viral pre-membrane or envelope (E) proteins, can potentially enhance dengue virus (DENV) infection. Although E...

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Detalles Bibliográficos

Principais autores:	Xinglong Liu, Zhengfeng Li, Xiaoxia Li, Weixuan Wu, Huadong Jiang, Yufen Zheng, Junjie Zhou, Xianmiao Ye, Junnan Lu, Wei Wang, Lei Yu, Yiping Li, Linbing Qu, Jianhua Wang, Feng Li, Ling Chen, Linping Wu, Liqiang Feng
Formato:	Artigo
Idioma:	Inglês
Publicado:	Nature Portfolio 2024-10-01
Series:	Nature Communications
Acceso en liña:	https://doi.org/10.1038/s41467-024-53242-0
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