A single-dose circular RNA vaccine prevents Zika virus infection without enhancing dengue severity in mice

Abstract Antibody-dependent enhancement (ADE) is a potential concern for the development of Zika virus (ZIKV) vaccines. Cross-reactive but poorly neutralizing antibodies, usually targeting viral pre-membrane or envelope (E) proteins, can potentially enhance dengue virus (DENV) infection. Although E...

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Principais autores:	Xinglong Liu, Zhengfeng Li, Xiaoxia Li, Weixuan Wu, Huadong Jiang, Yufen Zheng, Junjie Zhou, Xianmiao Ye, Junnan Lu, Wei Wang, Lei Yu, Yiping Li, Linbing Qu, Jianhua Wang, Feng Li, Ling Chen, Linping Wu, Liqiang Feng
格式:	Artigo
语言:	Inglês
出版:	Nature Portfolio 2024-10-01
丛编:	Nature Communications
在线阅读:	https://doi.org/10.1038/s41467-024-53242-0
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