A comparison of commercial assays quantifying mature brain-derived neurotrophic factor (mBDNF) and its precursor (pro-BDNF) in human serum

Abstract Brain-derived neurotrophic factor (BDNF) and its isoforms (pro- and mBDNF) are promising neurobiomarkers. While total serum BDNF levels have been previously validated, the newer isoforms have not. We aimed to identify the most common serum pro- and mBDNF assays through a literature search (...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Alicia Olivas-Martínez, Francisco M. Peinado, Ainhoa Pérez-Cantero, Lydia Espín-Moreno, Andrea Rodríguez-Carrillo, Esther García-Esquinas, Nicolás Olea, Vicente Mustieles, Mariana F. Fernández
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2025-10-01
coleção:	Scientific Reports
Assuntos:	Total BDNF Pro-BDNF MBDNF Serum Effect biomarkers ELISA
Acesso em linha:	https://doi.org/10.1038/s41598-025-22278-7
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!