Identifying potential ligand-receptor interactions by integrating LSTM network and the attention mechanism for cell-cell communication prediction

Abstract Background Cell-cell communication (CCC) mediated by ligand-receptor (L-R) interactions is fundamental to deciphering tissue development and disease mechanisms. While single-cell RNA sequencing (scRNA-seq) has advanced this field, existing computational methods for inferring CCC often suffe...

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Ngā kaituhi matua:	Yingwei Deng, Min Chen, Pengfei Gao, Ruogu Luo, Zejun Li, Yuhua Yao
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	BMC 2026-05-01
Rangatū:	Journal of Translational Medicine
Ngā marau:	Cell-cell communication Ligand-receptor interactions LSTM Attention mechanism Single-cell RNA sequencing
Urunga tuihono:	https://doi.org/10.1186/s12967-026-08033-0
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!