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Identifying potential ligand-receptor interactions by integrating LSTM network and the attention mechanism for cell-cell communication prediction

Abstract Background Cell-cell communication (CCC) mediated by ligand-receptor (L-R) interactions is fundamental to deciphering tissue development and disease mechanisms. While single-cell RNA sequencing (scRNA-seq) has advanced this field, existing computational methods for inferring CCC often suffe...

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Bibliografiske detaljer
Principais autores: Yingwei Deng, Min Chen, Pengfei Gao, Ruogu Luo, Zejun Li, Yuhua Yao
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2026-05-01
Serier:Journal of Translational Medicine
Fag:
Online adgang:https://doi.org/10.1186/s12967-026-08033-0
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