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A novel bi-directional promoter system allows tunable recombinant protein production in Pichia pastoris

Abstract Background The methylotrophic yeast Pichia pastoris is a well-studied host organism for recombinant protein production, which is usually regulated either by a constitutive promoter (e.g. promoter of glyceraldehyde-3-phosphate dehydrogenase; PGAP) or an inducible promoter (e.g. promoter of a...

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Autors principals: Vignesh Rajamanickam, Karl Metzger, Christian Schmid, Oliver Spadiut
Format: Artigo
Idioma:Inglês
Publicat: BMC 2017-09-01
Col·lecció:Microbial Cell Factories
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Accés en línia:http://link.springer.com/article/10.1186/s12934-017-0768-8
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