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Efficacy of NEMO-binding domain peptide used to treat experimental osteomyelitis caused by methicillin-resistant Staphylococcus aureus: an in-vivo study

Abstract Purpose Treatment of chronic osteomyelitis (bone infection) remains a clinical challenge. Our previous study had demonstrated that NEMO-binding domain (NBD) peptide effectively ameliorates the inhibition of osteoblast differentiation by TNF-α in vitro. In this work, NBD peptide was evaluate...

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Principais autores: Chang-Peng Xu, Ya Chen, Hong-Tao Sun, Zhuang Cui, Ya-Jun Yang, Lei Huang, Bin Yu, Fa-Zheng Wang, Qing-Po Yang, Yong Qi
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2019-11-01
Serier:Antimicrobial Resistance and Infection Control
Fag:
NBD peptide
Osteomyelitis
Methicillin-resistant Staphylococcus aureus
Vancomycin
Rabbit
Online adgang:http://link.springer.com/article/10.1186/s13756-019-0627-y
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