Efficacy of NEMO-binding domain peptide used to treat experimental osteomyelitis caused by methicillin-resistant Staphylococcus aureus: an in-vivo study

Abstract Purpose Treatment of chronic osteomyelitis (bone infection) remains a clinical challenge. Our previous study had demonstrated that NEMO-binding domain (NBD) peptide effectively ameliorates the inhibition of osteoblast differentiation by TNF-α in vitro. In this work, NBD peptide was evaluate...

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Hlavní autoři:	Chang-Peng Xu, Ya Chen, Hong-Tao Sun, Zhuang Cui, Ya-Jun Yang, Lei Huang, Bin Yu, Fa-Zheng Wang, Qing-Po Yang, Yong Qi
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2019-11-01
Edice:	Antimicrobial Resistance and Infection Control
Témata:	NBD peptide Osteomyelitis Methicillin-resistant Staphylococcus aureus Vancomycin Rabbit
On-line přístup:	http://link.springer.com/article/10.1186/s13756-019-0627-y
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