Transcription-replication conflicts as a source of common fragile site instability caused by BMI1-RNF2 deficiency.

Common fragile sites (CFSs) are breakage-prone genomic loci, and are considered to be hotspots for genomic rearrangements frequently observed in cancers. Understanding the underlying mechanisms for CFS instability will lead to better insight on cancer etiology. Here we show that Polycomb group prote...

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Váldodahkkit:	Anthony Sanchez, Angelo de Vivo, Peter Tonzi, Jeonghyeon Kim, Tony T Huang, Younghoon Kee
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Public Library of Science (PLoS) 2020-03-01
Ráidu:	PLoS Genetics
Liŋkkat:	https://doi.org/10.1371/journal.pgen.1008524
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