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Beyond the present: current and future perspectives on the role of infections in pediatric PCD

IntroductionPrimary Ciliary Dyskinesia (PCD) is a rare genetic disorder affecting motile cilia, leading to impaired mucociliary clearance and increased susceptibility to respiratory infections. These infections contribute to long-term complications such as bronchiectasis and lung function decline.Ob...

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Principais autores: Megan Frohlich, Bernadette Prentice, Louisa Owens, Shafagh Waters, Lucy Morgan
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2025-03-01
Serier:Frontiers in Pediatrics
Fag:
primary ciliary dyskinesia
acute infection
airway infection
exacerbation
bronchiectasis
airway remodeling
Online adgang:https://www.frontiersin.org/articles/10.3389/fped.2025.1564156/full
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