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Gene expression patterns vary in clonal cell cultures from Rett syndrome females with eight different MECP2 mutations

<p>Abstract</p> <p>Background</p> <p>Females with the neurological disorder Rett syndrome are heterozygous for mutations in X-linked MECP2 that encodes methyl-CpG binding protein 2 (MeCP2) thought to act as a transcriptional repressor. To identify target genes for MeCP2 modulation, we studied global...

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Autors principals: Lazzeroni Laura, Agarwal Priyanka, Traynor Jeff, Francke Uta
Format: Artigo
Idioma:Inglês
Publicat: BMC 2002-11-01
Col·lecció:BMC Medical Genetics
Accés en línia:http://www.biomedcentral.com/1471-2350/3/12
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