Cytogenetic Damages from Iododeoxyuridine -induced Radiosensitivity with and without Methoxyamine in Human Glioblastoma Spheroids

Objective: Iododeoxyuridine-induced Radiosensitivityi (IUdR) is ahalogenated thymidine analogue recognized to be effective in vitro andin vivo radiosensitizer in human cancers. It is reported that Methoxyamine (MX)potentiates DNA damages in cancer cells with blocking the repair pathway ofIUdR damage...

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Autori principali:	Ali Neshasteh-Riz, Mohammad Saki, Samideh Khoei
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Royan Institute (ACECR), Tehran 2008-01-01
Serie:	Cell Journal
Soggetti:	Radiosensitization Spheroid IUdR Methoxyamine BER
Accesso online:	http://celljournal.org/library/upload/article/Neshastehriz.pdf
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