Cytogenetic Damages from Iododeoxyuridine -induced Radiosensitivity with and without Methoxyamine in Human Glioblastoma Spheroids

Objective: Iododeoxyuridine-induced Radiosensitivityi (IUdR) is ahalogenated thymidine analogue recognized to be effective in vitro andin vivo radiosensitizer in human cancers. It is reported that Methoxyamine (MX)potentiates DNA damages in cancer cells with blocking the repair pathway ofIUdR damage...

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Principais autores:	Ali Neshasteh-Riz, Mohammad Saki, Samideh Khoei
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Royan Institute (ACECR), Tehran 2008-01-01
Colecção:	Cell Journal
Assuntos:	Radiosensitization Spheroid IUdR Methoxyamine BER
Acesso em linha:	http://celljournal.org/library/upload/article/Neshastehriz.pdf
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