Mtb-Timer: a fluorescent reporter to visualize Mycobacterium tuberculosis replication and antibiotic responses

ABSTRACT Despite the importance of monitoring Mycobacterium tuberculosis (Mtb) replication and antibiotic responses at the single-cell level, available tools to accurately monitor single Mtb replication are limited. Here, we report the development of Mtb-Timer, a fluorescent reporter in Mtb that exp...

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Detalhes bibliográficos

Principais autores:	Víctor Campo-Pérez, Chak Hon Luk, Laure Botella, Julien Vaubourgeix, Maximiliano G. Gutierrez
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology 2026-06-01
Colecção:	mSystems
Assuntos:	Mycobacterium tuberculosis single cell replication macrophages
Acesso em linha:	https://journals.asm.org/doi/10.1128/msystems.01796-25
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