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Mtb-Timer: a fluorescent reporter to visualize Mycobacterium tuberculosis replication and antibiotic responses

ABSTRACT Despite the importance of monitoring Mycobacterium tuberculosis (Mtb) replication and antibiotic responses at the single-cell level, available tools to accurately monitor single Mtb replication are limited. Here, we report the development of Mtb-Timer, a fluorescent reporter in Mtb that exp...

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Huvudupphov: Víctor Campo-Pérez, Chak Hon Luk, Laure Botella, Julien Vaubourgeix, Maximiliano G. Gutierrez
Materialtyp: Artigo
Språk:Inglês
Utgiven: American Society for Microbiology 2026-06-01
Serie:mSystems
Ämnen:
Mycobacterium tuberculosis
single cell
replication
macrophages
Länkar:https://journals.asm.org/doi/10.1128/msystems.01796-25
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