Integrated ICD-based subtyping and prognostic model reveal KCNN4 as a novel therapeutic target in NSCLC

Abstract Backgrounds Non-small cell lung cancer (NSCLC), the most common type of lung cancer, stands as a leading cause of cancer-related mortality worldwide. Immunogenic cell death (ICD )enhances cancer therapy efficacy by inducing immune responses and reshaping the TIME. While ICD increases cytoto...

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Principais autores:	Zhengzheng Yang, Qianru Yang, Shujiao Li, Ruiyang Han, Haiqiu He, Runze Zhang, Haiming Li, Yudong Li, Peiyu Cheng, Xiawei Liu
Format:	Artigo
Jezik:	Inglês
Izdano:	Springer 2026-02-01
Serija:	Discover Oncology
Teme:	Non-small cell lung cancer Immunogenic cell death Tumor microenvironment Prognostic model Molecular dynamics simulations
Online dostop:	https://doi.org/10.1007/s12672-026-04651-8
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