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Integrated ICD-based subtyping and prognostic model reveal KCNN4 as a novel therapeutic target in NSCLC

Abstract Backgrounds Non-small cell lung cancer (NSCLC), the most common type of lung cancer, stands as a leading cause of cancer-related mortality worldwide. Immunogenic cell death (ICD )enhances cancer therapy efficacy by inducing immune responses and reshaping the TIME. While ICD increases cytoto...

Täydet tiedot

Tallennettuna:
Päätekijät: Zhengzheng Yang, Qianru Yang, Shujiao Li, Ruiyang Han, Haiqiu He, Runze Zhang, Haiming Li, Yudong Li, Peiyu Cheng, Xiawei Liu
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer 2026-02-01
Sarja:Discover Oncology
Aiheet:
Non-small cell lung cancer
Immunogenic cell death
Tumor microenvironment
Prognostic model
Molecular dynamics simulations
Linkit:https://doi.org/10.1007/s12672-026-04651-8
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