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Beyond energy: how TCA cycle-derived metabolites regulate gene expression and inflammation in the nucleus

Abstract Immune cells can rewire their metabolism in response to various stimuli. Crosstalk between the nucleus and mitochondria allows for tight regulation of this metabolic reprogramming. Research has emerged showing several TCA cycle-derived metabolites exhibiting moonlighting functions in the nu...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Jaiya Randhawa, Eva M. Pålsson-McDermott
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BMC 2025-09-01
Sarja:Journal of Inflammation
Aiheet:
Linkit:https://doi.org/10.1186/s12950-025-00461-x
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