Automated in situ chromatin profiling efficiently resolves cell types and gene regulatory programs
Abstract Background Our understanding of eukaryotic gene regulation is limited by the complexity of protein–DNA interactions that comprise the chromatin landscape and by inefficient methods for characterizing these interactions. We recently introduced CUT&RUN, an antibody-targeted nuclease cleavage...
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| Principais autores: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2018-12-01
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| coleção: | Epigenetics & Chromatin |
| Assuntos: | |
| Acesso em linha: | http://link.springer.com/article/10.1186/s13072-018-0243-8 |
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