Mutations of PTPN11 are rare in adult myeloid malignancies
The PTPN11 gene encodes the phospho-tyrosyine phosphatase protein SHP-2. Constitutional mutations of this gene are involved in Noonan's syndrome, a developmental disorder in which children have a predisposition to develop a myeloid disorder called juvenile myelomonocytic leukemia. Recently, studies...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Ferrata Storti Foundation
2005-01-01
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| Schriftenreihe: | Haematologica |
| Online-Zugang: | https://haematologica.org/article/view/3565 |
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