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AKT inhibitors promote cell death in cervical cancer through disruption of mTOR signaling and glucose uptake.

<h4>Background</h4>PI3K/AKT pathway alterations are associated with incomplete response to chemoradiation in human cervical cancer. This study was performed to test for mutations in the PI3K pathway and to evaluate the effects of AKT inhibitors on glucose uptake and cell viability.<h4>Experimental d...

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Detaylı Bibliyografya
Asıl Yazarlar: Ramachandran Rashmi, Carl DeSelm, Cynthia Helms, Anne Bowcock, Buck E Rogers, Janet L Rader, Janet Rader, Perry W Grigsby, Julie K Schwarz
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science (PLoS) 2014-01-01
Seri Bilgileri:PLoS ONE
Online Erişim:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0092948&type=printable
Etiketler: Etiketle
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