AKT inhibitors promote cell death in cervical cancer through disruption of mTOR signaling and glucose uptake.

<h4>Background</h4>PI3K/AKT pathway alterations are associated with incomplete response to chemoradiation in human cervical cancer. This study was performed to test for mutations in the PI3K pathway and to evaluate the effects of AKT inhibitors on glucose uptake and cell viability.<h4>Experimental d...

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Egile Nagusiak:	Ramachandran Rashmi, Carl DeSelm, Cynthia Helms, Anne Bowcock, Buck E Rogers, Janet L Rader, Janet Rader, Perry W Grigsby, Julie K Schwarz
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Public Library of Science (PLoS) 2014-01-01
Saila:	PLoS ONE
Sarrera elektronikoa:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0092948&type=printable
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