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Human adenovirus oncolytic properties and the inhibitory role of E4 orf4 and E4 orf6/7 on endogenously activated NF-κB

Human adenovirus is a promising tool for cancer therapy as an oncolytic virus. To predict which region of the oncolytic adenovirus E4 gene could be deleted, we investigated the relationship between the E4 proteins and NF-κB. Here, we report that TLR2-dependent NF-κB activation in Ad5-infected cells...

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Detaylı Bibliyografya
Asıl Yazarlar: Anran Wang, Kazuki Uchida, Atsuro Yokoyama, Fumihiro Higashino, Motoaki Yasuda
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2024-03-01
Seri Bilgileri:Biochemistry and Biophysics Reports
Konular:
Online Erişim:http://www.sciencedirect.com/science/article/pii/S2405580823001978
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