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Human adenovirus oncolytic properties and the inhibitory role of E4 orf4 and E4 orf6/7 on endogenously activated NF-κB

Human adenovirus is a promising tool for cancer therapy as an oncolytic virus. To predict which region of the oncolytic adenovirus E4 gene could be deleted, we investigated the relationship between the E4 proteins and NF-κB. Here, we report that TLR2-dependent NF-κB activation in Ad5-infected cells...

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Xehetasun bibliografikoak
Egile Nagusiak: Anran Wang, Kazuki Uchida, Atsuro Yokoyama, Fumihiro Higashino, Motoaki Yasuda
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2024-03-01
Saila:Biochemistry and Biophysics Reports
Gaiak:
Sarrera elektronikoa:http://www.sciencedirect.com/science/article/pii/S2405580823001978
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