Disruption of the NDC80–Nek2 axis suppresses glioblastoma stemness and enhances therapeutic efficacy
Abstract Background Glioblastoma (GBM), the most aggressive primary brain tumor, demonstrates resistance to standard therapies, primarily due to the presence of GBM stem cells (GSCs), the mechanisms of which remain poorly understood. Methods To identify therapeutic targets for GSCs, we utilized mult...
שמור ב:
| Principais autores: | , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
BMC
2026-02-01
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| סדרה: | Journal of Translational Medicine |
| נושאים: | |
| גישה מקוונת: | https://doi.org/10.1186/s12967-026-07829-4 |
| תגים: |
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