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Harmine Inhibits Multiple TLR-Induced Inflammatory Expression through Modulation of NF-κB p65, JNK, and STAT1

Harmine is a beta-carboline alkaloid present in various plants, including in the seeds of <i>Peganum harmala</i> L. This study aimed to investigate the anti-inflammatory activity and mechanism of harmine using macrophages stimulated with various toll-like receptor (TLR) agonists and a model of endot...

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Principais autores: So-Jung Jin, Youngju Song, Hong Shik Park, Kye Won Park, SeungGwan Lee, Hee Kang
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2022-12-01
coleção:Life
Assuntos:
harmine
macrophages
TLR
inflammation
iNOS
TNF-α
Acesso em linha:https://www.mdpi.com/2075-1729/12/12/2022
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