Celastrol ameliorates osteoarthritis via regulating TLR2/NF-κB signaling pathway

Objectives: Osteoarthritis (OA) is a joint disease characterized by degeneration of joint cartilage and is a significant cause of severe joint pain, physical disability, and impaired quality of life in the aging population. Celastrol, a Chinese herbal medicine, has attracted wide interests because o...

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Autori principali:	Guangxia Yang, Kai Wang, Hua Song, Rujie Zhu, Shuai Ding, Hui Yang, Jian Sun, Xin Wen, Lingyun Sun
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2022-08-01
Serie:	Frontiers in Pharmacology
Soggetti:	osteoarthritis celastrol innate immunity TLR2 NF-κB
Accesso online:	https://www.frontiersin.org/articles/10.3389/fphar.2022.963506/full
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