Tgif1-deficiency impairs cytoskeletal architecture in osteoblasts by activating PAK3 signaling

Osteoblast adherence to bone surfaces is important for remodeling bone tissue. This study demonstrates that deficiency of TG-interacting factor 1 (Tgif1) in osteoblasts results in altered cell morphology, reduced adherence to collagen type I-coated surfaces, and impaired migration capacity. Tgif1 is...

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Autors principals:	Simona Bolamperti, Hiroaki Saito, Sarah Heerdmann, Eric Hesse, Hanna Taipaleenmäki
Format:	Artigo
Idioma:	Inglês
Publicat:	eLife Sciences Publications Ltd 2024-04-01
Col·lecció:	eLife
Matèries:	osteoblast spreading bone regeneration Tgif1 PAK3 PTH
Accés en línia:	https://elifesciences.org/articles/94265
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