Arsenic compounds activate MAPK and inhibit Akt pathways to induce apoptosis in MA‐10 mouse Leydig tumor cells

Abstract Arsenic compounds have been applied treating acute promyelocytic 1eukemia and solid tumors with brief mechanism investigations. In fact, we have demonstrated that sodium arsenite plus dimethylarsenic acid could activate apoptosis in MA‐10 mouse Leydig tumor cells by inducing caspase pathway...

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Hlavní autoři:	Wei‐Sheng Juan, Yi‐Fen Mu, Chia‐Yih Wang, Edmund‐Cheung So, Yi‐Ping Lee, Sheng‐Che Lin, Bu‐Miin Huang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Wiley 2023-02-01
Edice:	Cancer Medicine
Témata:	Akt dimethylarsenic acid Leydig tumor cell MAPK ROS sodium arsenite
On-line přístup:	https://doi.org/10.1002/cam4.5068
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