Arsenic compounds activate MAPK and inhibit Akt pathways to induce apoptosis in MA‐10 mouse Leydig tumor cells

Abstract Arsenic compounds have been applied treating acute promyelocytic 1eukemia and solid tumors with brief mechanism investigations. In fact, we have demonstrated that sodium arsenite plus dimethylarsenic acid could activate apoptosis in MA‐10 mouse Leydig tumor cells by inducing caspase pathway...

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Autores principales:	Wei‐Sheng Juan, Yi‐Fen Mu, Chia‐Yih Wang, Edmund‐Cheung So, Yi‐Ping Lee, Sheng‐Che Lin, Bu‐Miin Huang
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Wiley 2023-02-01
Colección:	Cancer Medicine
Materias:	Akt dimethylarsenic acid Leydig tumor cell MAPK ROS sodium arsenite
Acceso en línea:	https://doi.org/10.1002/cam4.5068
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